This guide combines three things most players look up separately in Resident Evil Requiem: opening safes (and not wasting resources doing it), completing Barry’s scavenger hunt in the RPD, and picking weapons that actually work together as a loadout. Use it as a checklist you can follow room-by-room or as a troubleshooting guide when you get stuck.

Before you start: a quick mindset that saves ammo

  • Safes are optional, but upgrades aren’t. Treat safes as “power spikes” (ammo, key items, weapon parts). Prioritize them when you’re low on supplies or about to face a tough section.
  • Don’t brute-force puzzles during danger windows. If you’re being pursued or resources are tight, retreat to a safe room, store excess items, and return with space to carry rewards.
  • Inventory space is the real currency. Plan a loop: collect quest items, open a safe on the way, then dump extras before the next wing.

How to open every safe (without memorizing everything)

Safes in Requiem typically reward you for exploration rather than guesswork. Even when a guide lists codes, it helps to know the logic behind them so you can find clues naturally on your own playthrough.

Step 1: Identify the safe type and what it “wants” from you

  • Dial/combination safe: usually expects a short numeric code found nearby (notes, plaques, desk memos).
  • Multi-stage safe/locker: may require a sequence (e.g., left-right-left), or multiple clues from different rooms.
  • Story-gated safe: appears early but is intended to be opened after you acquire a related key item or clearance.

Step 2: Search for “clue objects” in the immediate area

Before leaving the room, sweep for the common clue sources:

  • Handwritten notes, sticky notes, incident reports
  • Wall calendars, desk nameplates, award plaques
  • Whiteboards and filing labels (often hint at numbers or ordering)
  • Audio logs or readable terminals that mention “code”, “combination”, “locker”, or “safe”

Tip: If the room has multiple desks, check the undersides and drawers. Many horror games hide clue text on “secondary” interactables.

Step 3: Decide whether the safe is worth opening right now

Ask two questions:

  • Do I have 1–2 free inventory slots? If not, mark it on your map and return after a stash run.
  • Will the reward change my next 10 minutes? If you’re about to enter a new wing or boss-style encounter, it’s usually yes.

Step 4: Use a “safe loop” route in the RPD

When you’re in the RPD, safes are best tackled as part of a loop rather than as single trips:

  1. Start at the nearest safe room (save + storage).
  2. Clear a short corridor section (remove immediate threats).
  3. Collect the clue and open the safe on the same pass.
  4. Return to storage to bank upgrades/ammo before pushing deeper.

How to complete Barry’s scavenger hunt in the RPD

Barry’s scavenger hunt is easiest when you treat it like a route-planning exercise. The objective is rarely “hard” in isolation; what makes it frustrating is backtracking with limited healing/ammo and a full inventory.

Step 1: Prepare a scavenger-friendly inventory

  • Bring: one primary weapon, one backup weapon, a small amount of ammo for each, one heal, and one open slot.
  • Leave behind: crafting materials you’re not immediately using, duplicate healing items, and collectibles not tied to progression.
  • Rule of thumb: keep two free slots if you know the hunt rewards multiple items in a row.

Step 2: Read the hunt text like a riddle with “anchors”

Scavenger hunt steps commonly reference:

  • RPD landmarks: lobby, statues, reception, interrogation, records/archives, armory-style rooms
  • Directional language: “west wing”, “upper floor”, “behind”, “under”, “facing”
  • Object categories: clocks, plaques, display cases, filing cabinets

When you get a clue, identify the landmark first (where), then the interaction (what to do there).

Step 3: Clear the route, not the whole station

Instead of wiping every room, only make your path safe enough to run it twice:

  • Remove enemies that block narrow hallways or doorways.
  • Ignore enemies in large rooms you can sprint through safely.
  • If a pursuer-type threat is present, prioritize opening shortcuts (doors, ladders, hallway connectors).

Step 4: Use map marking and “return triggers”

  • Mark any locked doors tied to scavenger steps so you don’t forget to revisit them after you find the key item.
  • Return to storage when you obtain a unique quest item (don’t risk losing it to a death + reload loop).

Common scavenger hunt pitfalls (and fixes)

  • Pitfall: You find the next item but can’t pick it up. Fix: stash a non-essential stack (extra ammo/craft) and come back immediately.
  • Pitfall: You keep revisiting the same locked barrier. Fix: the hunt often chains into a safe/locker clue—check nearby notes again after each step.
  • Pitfall: You’re burning too much ammo. Fix: switch your primary to something that staggers reliably; save high-damage rounds for unavoidable encounters.

Weapons and loadout: what to carry and why

A strong loadout isn’t “the strongest gun”; it’s a set that covers different problems: single-target control, crowd pressure, and emergency burst damage.

Recommended all-purpose loadout (early to mid game)

  • Primary handgun (control): for consistent headshots, resource efficiency, and finishing staggered enemies.
  • Shotgun or close-range heavy (panic button): for stopping power at short distance when you misposition.
  • Precision option (utility): a weapon or attachment that helps with weak points at medium range (depends on what you’ve unlocked).

How to choose between two weapons that feel similar

  • Pick higher stagger, not higher raw damage, if you’re often forced into tight hallways (like the RPD).
  • Pick better ammo availability if you’re exploring and opening safes frequently; you’ll spend longer between saves and need reliability.
  • Pick faster handling/reload if the game features pressure enemies or chase segments.

Upgrade priorities (so you don’t regret your parts)

  1. Capacity/reload for your primary (keeps you alive in long corridors).
  2. Stability/accuracy (reduces wasted rounds).
  3. Damage (best once you’re already landing shots consistently).

Note: Safe rewards often include the kind of parts that make these upgrades possible—another reason to fold safe runs into your scavenger route.

A simple “one run” plan for the RPD section

  1. Start from a safe room with 1–2 free inventory slots.
  2. Follow Barry’s clue to the next landmark and collect the hunt item.
  3. On the way back, detour to any safe whose clue you already have and open it.
  4. Bank items, restock, then push to the next scavenger step.
  5. If you hit a locked progression gate, stop and do a safe-opening loop in nearby rooms to power up before forcing the next encounter.

Troubleshooting

  • I can’t find the safe code clue. Re-check the nearest desks/noticeboards and any newly unlocked adjacent room; clues are often placed just beyond the first lock.
  • I’m stuck on a scavenger step. Read the clue again and identify the landmark noun (e.g., “statue”, “clock”, “records”). Then search only that category of rooms on the map.
  • My weapons feel weak. Shift upgrades to handling/capacity first and keep a two-weapon setup that covers both control and burst damage.

If you want, share which RPD scavenger step you’re on (the exact clue text) and what weapons you currently have, and I’ll suggest the fastest route and a loadout tweak without spoilers beyond the next objective.